Got Type 2 diabetes?
1 in 2 people with type 2 diabetes will develop chronic kidney disease (CKD).
An advanced predictive blood test that identifies your risk of CKD up to 4 years before irreversible damage begins.
Order test online. No waiting rooms
Blood test results in 14 days
Get clarity on your kidney future, act sooner
Keep your kidneys healthy for longer
The current model of care is not good enough.
The current model of care is not good enough.
Promarker®D correctly identified 86% of low risk patients who progressed to CKD, years before traditional tests like eGFR or ACR showed any signs of damage1,2.
Early detection is the critical difference
If you have type 2 diabetes, your doctor may be monitoring your kidneys with traditional tests like eGFR or ACR, but these only detect damage after it’s already occurred. This leaves many facing serious and invasive treatments like dialysis or transplant.
How to purchase Promarker®D, $390 USD
1
Check Your Eligibility
Answer a few quick health questions online. If you're eligible, you can order your test right away.
2
Get Medical Authorization
Fill out a quick online intake form. A U.S.-licensed doctor will review it and approve your test if it’s right for you.
3
Standard Blood Draw
Book an appointment at our participating collection centre. Bring your test requisition form with you on the day
4
Get Answers In Days
You’ll get an email when your results are ready, usually within 2 weeks from blood collection. You can book a follow-up consult with our doctors or talk to your own provider.
This test is conducted in a CLIA-certified diagnostic testing laboratory.
Risk-free Guarantee
If deemed clinically ineligible, at any stage, receive a $390 refund for the test, no questions asked.
Promarker®D is a proactive breakthrough test that predicts CKD risk before damage begins.
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Standard Tests
Developed by Proteomics International
Its founder, Dr Richard Lipscombe, is a global leader in the field of proteomics—the study of proteins to better understand disease. With over 25 years of experience in both academic research and biotech innovation, his expertise in mass spectrometry has helped transform how we detect disease before symptoms appear.
Diabetic kidney disease is a major public health challenge, and PromarkerD offers a highly innovative, accurate, and accessible way to identify those most at risk. By enabling proactive management, we aim to reduce the personal and financial costs associated with this life-threatening condition.
Dr Richard Lipscombe
Managing Director, Proteomics International
Proteomics International, a trusted Australian medical technology company operating at the forefront of precision diagnostics, specializing in advanced protein science to improve disease diagnosis and patient care.
Watch the story of Promarker®D
Diabetes test receives national recognition
“Highlighted as the most prominent translational outcome in diabetes research.”
Proactively changing renal healthcare
The Science behind Promarker®D
Predicts your risk of kidney disease up to 4 years before symptoms appear
People with a 'high risk' result by Promarker®D are 13.5x more likely to develop kidney disease than a 'low risk' result
Proven to predict kidney disease risk with 86% accuracy
You have questions, we have answers
Easy to access, and even easier to understand.
What is this test?
1 in 2 people with type 2 diabetes will develop chronic kidney disease, which can lead to dialysis or a transplant3,4,5.
The Promarker®D test can predict your risk of kidney disease years for up to 4 years before symptoms appear. Early detection helps you and your doctor take action to delay or prevent its progression.
Although your doctor may have you taking regular kidney function tests such as eGFR or ACR, these tests do not predict the onset of kidney disease.
Studies show the test is 86% accurate in predicting kidney disease. Patients identified as "high risk" by the test are 13.5 times more likely to develop kidney disease up to 4 years in advance6,7.
The Promarker®D test also helps doctors choose treatments. Patients at high risk benefit most from kidney-protecting drugs, and doctors use the results to adjust medications and monitor patients more closely8,9.
Who should take the test?
Promarker®D test is suitable for adults who have been diagnosed with diabetes (type 2) by a health professional and have an eGFR of greater than 30 mL/min/1.73m2.
What does the test measure?
The Promarker®D works by measuring protein biomarkers in your blood that are linked with kidney disease.
A scientifically proven algorithm combines these results with data about your age and eGFR (a kidney function measure). It then calculates how likely it is you will develop kidney disease in the next 4 years.
When should I do the test?
If you’re eligible, it’s never too early to take the test. In fact, early detection of kidney disease may help to slow or stop disease progression and reduce the complications associated with it10. Knowing your risk helps you and your doctor develop a plan to keep your kidneys healthy for as long as possible.
What to expect with your results?
The Promarker®D test algorithm works out a score indicating how likely it is your kidney function will decline over the next 4 years. It uses a traffic light system to classify your risk. The diabetic kidney disease test algorithm works out a score indicating how likely it is your kidney function will decline over the next 4 years. It uses a traffic light system to classify your risk.
• Green = low risk of kidney disease
• Amber = moderate risk of kidney disease
• Red = high risk of kidney disease
What happens after I get my result?
You and your ordering physician will receive a copy of the test results.
You can opt to book a telehealth follow up consult to discuss your results or share your results with your regular doctor (managing clinician).
With this test report, your doctor can work with you to create a treatment plan to help keep your kidneys healthy for as long as possible.
Depending on the results, your doctor might suggest:
• lifestyle changes such as healthy eating, managing your weight and quitting smoking
• more frequent monitoring
• avoiding medicines that can damage the kidneys
• prescribing medication designed to protect kidney function
What is type 2 diabetes?
Type 2 diabetes is a condition that affects your body’s ability to make and use insulin, a hormone that helps to regulate your blood sugar levels. This leads to a build-up of glucose (a type of sugar) in your bloodstream, leading to high blood sugar levels. Unless type 2 diabetes is well managed, the high blood sugar levels can lead to complications including heart disease, kidney damage, nerve damage, and vision problems.
What is diabetic kidney disease?
Diabetic kidney disease (DKD), also known as diabetic nephropathy, is a complication of diabetes. It affects the kidneys' ability to filter waste materials from the blood. Over time, high blood sugar levels can damage the small blood vessels and structures in the kidneys, leading to reduced kidney function. In severe cases, this can result in kidney failure.
What is chronic kidney disease?
Chronic Kidney Disease (CKD) is a long-term condition where the kidneys gradually lose their ability to filter waste and excess fluid from the blood, often without noticeable symptoms in the early stages. If left unmanaged, CKD can lead to serious complications such as high blood pressure, anaemia, heart disease, and eventually kidney failure. It’s commonly caused by conditions like diabetes and high blood pressure, and is diagnosed through blood and urine tests. While CKD can’t always be reversed, early detection and lifestyle changes can help slow its progression and reduce the risk of complications.
What is eGFR?
Estimated glomerular filtration rate (eGFR) is a measure of how well your kidneys are filtering waste from your blood. It is calculated based on your age, gender, and the level of creatinine in the blood. eGFR results help healthcare providers assess kidney function.
Am I eligible for the test?
To be eligible, you must:
• be 18 years of age or older
• have a diagnosis of type 2 diabetes from a healthcare professional
• have an eGFR greater than 30 ml/min/1.73m2
Can I get a refund if it turns out I’m not eligible?
Yes, we will fully refund your purchase if the Telehealth physician determines you are not eligible for the test.
How do I do the test?
Follow these simple steps to take the Promarker®D test.
1. Purchase the test online above.
2. Download the test requisition form and book an appointment at a participating collection center.
3. Take the test requisition form to a participating collection center and have your blood sample taken.
4. Your results will be sent to you and your referring physician.
How much does it cost and can I get a Medicare rebate?
The Promarker®D test is priced at $390 USD and is currently not covered by reimbursement. It is available as a self-pay option only.
How long until I get my results?
Up to 14 days depending on where you are located.
Do I need a doctor's referral?
You don’t need a referral from your usual doctor to do the Promarker®D test. Our platform connects you to physicians who can authorize the test requisition for you. The cost of this physician is included in the purchase price.
How often should I take the test?
This depends on your results. Current clinical recommendations suggest the following:
• Low Risk - every 4 years
• Moderate Risk - every 2 years
• High Risk - as determined by your doctor
Are my results and personal details kept private?
We know health information is sensitive and take your privacy very seriously. Your test results are private and confidential – only you and your referring doctor have access to them. We store your personal information on highly secure, encrypted servers and will never share your information with third parties without your permission. See our Privacy Policy for further information.
The cost of the status quo
Acting now means investing in your health now and preventing potentially large, future expenses and significant impacts on your life.
Don’t wait! Knowledge is power
This test offers a unique advantage for individuals living with type 2 diabetes. Early insight about your kidney health means:
Enjoy less worry and anxiety with a clearer understanding.
Have more time to act to maintain your health and lifestyle.
Proactive actions to avoid dialysis and kidney failure in the future.
References
- Peters et al., 2025. Next-Generation PromarkerD vs. Standard of Care for Assessing Kidney Function Decline in Type 2 Diabetes. American Diabetes Association Late-Breaking Poster. June 20-23. Chicago, IL. Diabetes 13 June 2024; 74 (Supplement_1): 1862-LB. https://doi.org/10.2337/db25-1862-LB
- Peters KE, Joubert IA, Bringans SD, Davis WA, Lipscombe RJ, Davis TME, PromarkerD Versus Standard of Care Biochemical Measures for Assessing Future Renal Function Decline in Type 2 Diabetes, Diagnostics 2025:15(6):662
- Thomas MC, et al. Diabetic kidney disease. Nat Rev Dis Primers. 2015;1:15018. Published 2015 Jul 30. doi:10.1038/nrdp.2015.18.
- International Diabetes Federation 2021.
- de Boer, Ian H et al. Diabetes Management in Chronic Kidney Disease: A Consensus Report by the American Diabetes Association (ADA) and Kidney Disease: Improving Global Outcomes (KDIGO). Diabetes care vol. 45,12 (2022): 3075-3090. doi:10.2337/dci22-0027.
- Peters KE, et al. Validation of a protein biomarker test for predicting renal decline in type 2 diabetes: The Fremantle Diabetes Study Phase II. J Diab Comp. 2019.
- Peters KE, et al. Diabetic kidney disease test Predicts Renal Function Decline in Type 2 Diabetes in the Canagliflozin Cardiovascular Assessment Study (CANVAS). Journal of Clinical Medicine. 2020.
- Peters KE, et al. Canagliflozin Attenuates Diabetic kidney disease test Diabetic Kidney Disease Risk Prediction Scores, Journal of Clinical Medicine. 2023.
- Fusfeld L, et al. Evaluation of the Clinical Utility of Diabetic kidney disease test In-Vitro Test in Predicting Diabetic Kidney Disease and Rapid Renal Decline. PLOS ONE. 2022.
- UpToDate. Early detection of chronic kidney disease. Available at https://www.uptodate.com/contents/early-detection-of-chronic-kidney-disease. Accessed 5 Dec 2024.